|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Proto-Oncogene Proteins c-bcr
|
|
Descriptor Spanish:
|
|
Proteínas Proto-Oncogénicas c-bcr
|
|
Descriptor Portuguese:
|
|
Proteínas Proto-Oncogênicas c-bcr
|
|
Synonyms English:
|
|
Breakpoint Cluster Region Protein
Proto-Oncogene Protein bcr
Proto-Oncogene Protein c-bcr
c-bcr Proto-Oncogene Proteins
Proto Oncogene Protein bcr
Proto Oncogene Protein c bcr
Proto Oncogene Proteins c bcr
Proto-Oncogene Proteins, bcr
Proto-Oncogene Proteins, c-bcr
bcr Proto Oncogene Proteins
c bcr Proteins
c bcr Proto Oncogene Proteins
c-bcr, Proto-Oncogene Protein
c-bcr, Proto-Oncogene Proteins
bcr Proto-Oncogene Proteins
c-bcr Proteins
|
|
Tree Number:
|
|
D08.811.913.696.620.682.700.759
D12.644.360.325.300.099.500
D12.776.476.325.300.099.500
D12.776.624.664.700.171
|
|
Definition English:
|
|
A serine-threonine kinase that contains a C2 DOMAIN and PLECKSTRIN HOMOLOGY DOMAIN. It also has activity as a GTPASE-ACTIVATING PROTEIN for RAC1 PROTEIN and CDC42 PROTEIN. It functions as a negative regulator of CELL PROLIFERATION and NEOPLASTIC CELL TRANSFORMATION and is commonly fused with cellular abl protein to form BCR-ABL FUSION PROTEINS in PHILADELPHIA CHROMOSOME positive LEUKEMIA patients. |
|
History Note English:
|
|
2006(1988)
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
50725
|
|
Unique Identifier:
|
|
D051562
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|